ParthasarathyLab

           Biophysics & Soft Condensed Matter

Description

The image shows the fluorescence emission from a lipid membrane with membrane-anchored polymers assembled on a terraced substrate that enables the use of "fluorescence interference contrast microscopy," a technique by which the interference of light from fluorophores with its reflection from a substrate can yield nanometer-scale topographic information. The colors are due to different interference patterns from emission from red lipid-conjugated probes and green polymer-conjugated probes. The image width is about 200 microns. Further information, including analysis of this data, can be found in our recent paper: Kamil Godula, Marissa L. Umbel, David Rabuka, Zsofia Botyanszki, Carolyn R. Bertozzi, and Raghuveer Parthasarathy, "Control of the molecular orientation of membrane-anchored biomimetic glycopolymers," J. Am. Chem. Soc. 131: 10263-10268 (2009). http://pubs.acs.org/doi/abs/10.1021/ja903114g

Nat Chem Bio cover

 

2010 -- Raghuveer Parthasarathy, University of Oregon, Department of Physics and Materials Science Institute.

Unauthorized duplication of images is strictly prohibited!

Contact:  raghu [at] uoregon.edu

Last updated: July 1, 2010